Introduction: Over the past a few decades, human societies have observed that the concentrations of heavy metals in the environment have increased due to industrial development, mining exploration, smelting industries and sometimes due to accidental emissions. These activities have posed a major threat to the human’s health. Industrial towns are among the centers that, if not adequately monitored, can lead to the dispersion of heavy metals in the environment and endanger the health of people living in the surrounding area. Materials and Methods: For this purpose, the environmental hazards of wastewater from Charm-Shahr industrial town were investigated. In this study, the Risk Assessment Information System (RAIS) web-based software was used. The measured wastewater samples were analyzed between 2004 and 2019 and after pollutants’ identifications, non-carcinogenic hazards and carcinogenic risks of the human’s exposure to those pollutants were evaluated. Results:Based on the sampling from the outlet of Charm-Shahr’s water treatment plant, in most cases, the non-carcinogenic risk of exposure to the contaminants in water was less than 1, indicating that there is no significant risk to the residents in relation to the surface water of the exposure area. In one case, the non-carcinogenic risk of exposure to the contaminants in water from the oral path was in the range of 0.1 Discussion: According to the results, this risk was due to exposure to hexavalent chromium which was found in the sewage due to the presence of leather industries in Cahrm-Shahr. The rate of carcinogenic risk from both oral and skin pathways were in the range of and . Therefore, there was a possibility of carcinogenesis in relation to the contaminants. The total risk was also in the range of and , indicating the risk of total carcinogenesis was definite or probable, and in some cases, there was no known risk. Results showed that the existing health risk was due to the presence of hexavalent chromium and in some cases was related to nickel. It has been reported that chromium is sometimes converted to stable compounds with higher toxicity in the natural environment. In this study, we discussed the risk assessment due to the exposure of different groups of people and the impact on their health due to the concentrations of heavy metals resulting from industrial activities. The findings show that the carcinogenic risk was due to the presence of hexavalent chromium and in some cases nickel. The possibility of non-carcinogenic hazards and carcinogenic risks of exposure to hexavalent chromium and nickel were possible, probable and in some cases definite. Therefore, it is necessary to monitor the functionality of the Charm-Shahr’s water treatment plant and track the number of pollutants at specific time intervals. Periodic and continuous measurements of pollutants and the risk assessment due to the presence of hexavalent chromium and nickel pollutants on fish, other animals and plants in the region can be useful in controlling environmental pollution, providing monitoring programs and regional decision-making.
Ahmadi Moshiran, V., Karimi, A., Golbabaei, F., Sadeghi Yarandi, M., Asghar Sajediyan, A. and Ghasemi Koozekonan, A., 2020. Evaluating occupational exposure to Styrene vapor and determining risks of health consequences in Petrochemical Industry Workers. Journal of health and safety at work.10 (4), 316-328. [In Persain].
Adamu, C.I., Nganje, T.N. and Edet, A., 2015. Heavy metal contamination and health risk assessment associated with abandoned barite mines in Cross River State, southeastern Nigeria. Environmental Nanotechnology, monitoring & management. 3, 10-21.
Aein Jamshid, K. and Haghshenas, A., 2017. Environmental risk assessment of the activity of SPE shrimp production centers. Iranian scientific fisheries journal. 26(4), 73-81. [In Persain].
Ali, H. and Khan, E., 2019. Trophic transfer, bioaccumulation, and biomagnification of non-essential hazardous heavy metals and metalloids in food chains/webs—Concepts and implications for wildlife and human health. Human and Ecological Risk Assessment: An International Journal. 25(6), 1353-1376.
Alves, R.I., Sampaio, C.F., Nadal, M., Schuhmacher, M., Domingo, J.L. and Segura-Muñoz, S.I., 2014. Metal concentrations in surface water and sediments from Pardo River, Brazil: human health risks. Environmental research.133, 149-155.
ATSDR (Agency for Toxic Substances and Disease Registry). 2005. Public health statement nickel, CAS#: 7440-02-0, summary chapter from the toxicological profile for nickel. Department of Health and Human Services, Public Health Service Agency for Toxic Substances and Disease Registry. http://www.atsdr.cdc.gov/.
Azimi-Yancheshmeh, R., Moeinaddini, M., Mazloomi, S., Feyz Nia, S. and Shahbazi, R., 2022. Health risk assessment of metals in street dust of Karaj City in 2018. Journal of environmental health engineering. 9 (3), 313-332. [In Persain].
Cao, S., Duan, X., Ma, Y., Zhao, X., Qin, Y., Liu, Y., ... and Wei, F., 2017. Health benefit from decreasing exposure to heavy metals and metalloid after strict pollution control measures near a typical river basin area in China. Chemosphere. 184, 866-878.
Chen, L., Zhou, S., Shi, Y., Wang, C., Li, B., Li, Y. and Wu, S., 2018. Heavy metals in food crops, soil, and water in the Lihe River Watershed of the Taihu Region and their potential health risks when ingested. Science of the total environment. 615, 141-149.
Chowdhury, M., Mostafa, M.G., Biswas, T.K., Mandal, A. and Saha, A.K., 2015. Characterization of the effluents from leather processing industries. Environmental Processes. 2(1), 173-187.
Dandira, V., Mugwindiri, K. and Chikuku, T., 2012. A cleaner production exercise of a leather manufacturing company: a Zimbabwean experience. International Journal of Scientific & Technology Research. 1(11), 1-5.
De Aquim, P.M., Hansen, É. and Gutterres, M., 2019. Water reuse: An alternative to minimize the environmental impact on the leather industry. Journal of environmental management. 230, 456-463.
Duffus, J.H., 2002. “Heavy metals" a meaningless term? (IUPAC Technical Report). Pure and applied chemistry. 74 (5), 793-807.
Ehtemae, N., Ghanavati, N., Nazarpour, A., Babaenejad, T.and James Watts, M., 2020. Assessment of Potential Ecological and Human Health Risk of Some Selected Heavy Metals in Street Dusts in Ilam. Journal of Water and Soil Science. 23 (4), 183-197. [In Persain].
Engwa, G.A., Ferdinand, P.U., Nwalo, F. N. and Unachukwu, M.N., 2019. Mechanism and health effects of heavy metal toxicity in humans. Poisoning in the modern world-new tricks for an old dog,
Feng, H., Jiang, H., Gao, W., Weinstein, M.P., Zhang, Q., Zhang, W. ... and Tao, J., 2011. Metal contamination in sediments of the western Bohai Bay and adjacent estuaries, China. Journal of Environmental Management. 92(4), 1185-1197.
Hedayatzadeh, F. and Hassanzadeh, N., 2020. Evaluation of Heavy Metal Contamination and Ecological Risk Assessment in Sediments of Karun using Aquatic Pollution Indices. Archives of Hygiene Sciences. 9(1), 10-26.
Herojeet, R., Rishi, M.S. and Kishore, N., 2015. Integrated approach of heavy metal pollution indices and complexity quantification using chemometric models in the Sirsa Basin, Nalagarh valley, Himachal Pradesh, India. Chinese Journal of Geochemistry. 34 (4), 620-633.
Hutton, M. and Shafahi, M., 2019. Water pollution and leather industry-A review.13th International Conference on Energy Sustainability, Bellevue, WA, USA.
Joshi, J.B., Mahajani, V.V. and Juvekar, V.A., 1985. Invited review absorption of NOx gases. Chemical Engineering Communications. 33(1-4), 1-92.
Ishtiaq, M., Khan, M.J., Khan, S.A., Ghani, J., Ullah, Z., Nawab, J. ... and Alharbi, S.N., 2024. Potentially harmful elements and health risk assessment in groundwater of urban industrial areas. Frontiers in Environmental Science. 12, 1332965.
Kanagaraj, G. and Elango, L., 2019. Chromium and fluoride contamination in groundwater around leather tanning industries in southern India: Implications from stable isotopic ratio δ53Cr/δ52Cr, geochemical and geostatistical modelling. Chemosphere. 220, 943-953.
Karimi, S.R., Mansouri, N., Taghavi, L. and Moeinaddini M., 2022. Carcinogenicity and non-carcinogenicity risk assessment encounter of air heavy metals. Journal of environmental science and technology. 24(6), 77-90. [In Persain].
Kato, S. and Kansha, Y., 2024. Comprehensive review of industrial wastewater treatment techniques. Environmental Science and Pollution Research, 31(39), 51064-51097.
Kumar, V., Sharma, A., Kumar, R., Bhardwaj, R., Kumar Thukral, A. and Rodrigo-Comino, J., 2020. Assessment of heavy-metal pollution in three different Indian water bodies by combination of multivariate analysis and water pollution indices. Human and ecological risk assessment: an international journal. 26(1), 1-16.
Lefebvre, O. and Moletta, R., 2006. Treatment of organic pollution in industrial saline wastewater: a literature review. Water research. 40(20), 3671-3682.
Li, F., Qiu, Z., Zhang, J., Liu, W., Liu, C. and Zeng, G., 2017. Investigation, pollution mapping and simulative leakage health risk assessment for heavy metals and metalloids in groundwater from a typical brownfield, middle China. International journal of environmental research and public health. 14(7), 768.
Mirbagheri, S.A., Shams, A., Hashemi, S.H.and Shams, H., 1387. Removal of divalent nickel from wastewater of electroplating industries by reverse osmosis method. Environmental Science and Technology.12(1): 1-11. [In Persain].
Mishra, S., Chowdhary, P. and Bharagava, R.N., 2019. Conventional methods for the removal of industrial pollutants, their merits and demerits. In Emerging and eco-friendly approaches for waste management(pp. 1-31). Springer, Singapore.
Nanda, M., Kumar, V. and Sharma, D.K., 2019. Multimetal tolerance mechanisms in bacteria: The resistance strategies acquired by bacteria that can be exploited to ‘clean-up’heavy metal contaminants from water. Aquatic toxicology. 212, 1-10.
Nur-E-Alam, M., Mia, M.A.S., Ahmad, F. and Rahman, M.M., 2020. An overview of chromium removal techniques from tannery effluent. Applied Water Science. 10 (9), 1-22.
Okafor, C.O., Ude, U.I., Okoh, F.N. and Eromonsele, B.O., 2024. Safe drinking water: The need and challenges in developing countries. In Water quality-new perspectives. IntechOpen
Ouyang, Y., Higman, J., Thompson, J., O'Toole, T. and Campbell, D., 2002. Characterization and spatial distribution of heavy metals in sediment from Cedar and Ortega rivers subbasin. Journal of Contaminant Hydrology. 54(1-2), 19-35.
Parsajou, H. and Nasrabadi, T., 2021. Evaluation of greenhouse gases emission and human health risk levels due to operation and maintenance of Sareyn City wastewater treatment plant. Journal of environmental studies. 47(1): 45-64. [In Persain].
Rashidi Fard, M., Rashidi, Y. and Amiri, M., 2019. Modeling the emission and calculation of the risk of steelmaking contaminants using the AERMOD model. Journal of Behdasht Dar Arseh (i.E., Health in the Field). 6(3), 27–35. [In Persain].
Romero-Crespo, P., Jiménez-Oyola, S., Salgado-Almeida, B., Zambrano-Anchundia, J., Goyburo-Chávez, C., González-Valoys, A. and Higueras, P., 2023. Trace elements in farmland soils and crops, and probabilistic health risk assessment in areas influenced by mining activity in Ecuador. Environmental Geochemistry and Health. 45(7), 4549-4563.
Saghi, G., 2000. Feasibility study of wastewater treatment and wastewater circulation in small industrial communities (Charm-Shahr, Mashhad). Master's thesis, Faculty of Civil Engineering, Iran University of Science and Technology, Tehran, Iran. [In Persain].
Saidon, N.B., Szabó, R., Budai, P. and Lehel, J., 2024. Trophic transfer and biomagnification potential of environmental contaminants (heavy metals) in aquatic ecosystems. Environmental pollution, 340, 122815.
Sajil Kumar, P.J. and James, E.J., 2019. Assessing the impact of leather industries on groundwater quality of Vellore District in South India using a geochemical mixing model. Environmental Claims Journal. 31(4), 335-348.
Sawalha, H., Alsharabaty, R., Sarsour, S. and Al-Jabari, M., 2019. Wastewater from leather tanning and processing in Palestine: characterization and management aspects. Journal of environmental management.251, 109596.
Tamersit, S., Bouhidel, K.E. and Zidani, Z., 2018. Investigation of electrodialysis anti-fouling configuration for desalting and treating tannery unhairing wastewater: Feasibility of by-products recovery and water recycling. Journal of environmental management. 207, 334-340.
Tiwari, A.K. and De Maio, M., 2017. Assessment of risk to human health due to intake of chromium in the groundwater of the Aosta Valley region, Italy. Human and Ecological Risk Assessment: An International Journal. 23(5), 1153-1163.
USEPA., 2004. Risk assessment guidance for superfund volume i: human health evaluation manual (part e, supplemental guidance for dermal risk assessment). Office of superfund remediation and technology innovation, U.S. Environmental protection agency. Washington, D C.
Wanjiya, M., Zhang, J.C., Wu, B., Yin, M.J. and An, Q.F., 2024. Nanofiltration membranes for sustainable removal of heavy metal ions from polluted water: A review and future perspective. Desalination, 578, 117441.
Wu, H., Liao, Q., Chillrud, S.N., Yang, Q., Huang, L., Bi, J. and Yan, B., 2016. Environmental exposure to cadmium: health risk assessment and its associations with hypertension and impaired kidney function. Scientific reports, 6(1), 1-9.
Yadav, A., Chowdhary, P., Kaithwas, G. and Bharagava, R.N., 2017. Toxic Metals in the Environment: Threats on Ecosystem and Bioremediation Approaches. In Handbook of Metal-Microbe Interactions and Bioremediation (pp. 128-141). CRC Press.
Yaqoob, A.A., Parveen, T., Umar, K. and Mohamad Ibrahim, M.N., 2020. Role of nanomaterials in the treatment of wastewater: A review. Water, 12(2), 495.
Zainith, S.U.R.A.B.H.I., Sandhya, S., Saxena, G.A.U.R.A.V. and Bharagava, R.N., 2016. Microbes an ecofriendly tool for the treatment of industrial waste waters. Microbes and Environmental Management. 78-103.
Khojasteh,S. and Karimi,A. (2024). Health Risk Assessment Due to Wastewater in Charm-Shahr Industrial Town of Mashhad. Environment and Interdisciplinary Development, 9(86), 106-120. doi: 10.22034/envj.2025.492282.1442
MLA
Khojasteh,S. , and Karimi,A. . "Health Risk Assessment Due to Wastewater in Charm-Shahr Industrial Town of Mashhad", Environment and Interdisciplinary Development, 9, 86, 2024, 106-120. doi: 10.22034/envj.2025.492282.1442
HARVARD
Khojasteh S., Karimi A. (2024). 'Health Risk Assessment Due to Wastewater in Charm-Shahr Industrial Town of Mashhad', Environment and Interdisciplinary Development, 9(86), pp. 106-120. doi: 10.22034/envj.2025.492282.1442
CHICAGO
S. Khojasteh and A. Karimi, "Health Risk Assessment Due to Wastewater in Charm-Shahr Industrial Town of Mashhad," Environment and Interdisciplinary Development, 9 86 (2024): 106-120, doi: 10.22034/envj.2025.492282.1442
VANCOUVER
Khojasteh S., Karimi A. Health Risk Assessment Due to Wastewater in Charm-Shahr Industrial Town of Mashhad. Environment and Interdisciplinary Development, 2024; 9(86): 106-120. doi: 10.22034/envj.2025.492282.1442